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When cranky about the medical industry, I've been known to comment, "More people have been saved from disease by illiterate ditchdiggers than all the doctors who've ever lived."

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You might find this article about drugs for ALS interesting. They explicitly make parallels between ALS drugs with poor evidence and Alzheimer’s drugs. https://www.newyorker.com/magazine/2023/06/26/relyvrio-als-fda-approval

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I'll do you one better on the interesting front. Take a look at the last name of the CEO quoted in the article...

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